For more than 85 years since the founding of Samarkand State Medical Institute, the staff of the Department of Hospital Therapy has carried out extensive scientific and pedagogical activity institute-wide, providing specialized medical care to the population of Samarkand region, training and educating qualified medical personnel, and researching pressing scientific and practical problems. Over this period, the department has been shaped by the efforts of several generations of scientists and physicians, forming its own scientific school. As department leadership changed over the years, its scientific directions expanded as well, with clinical practice and fundamental research developing in close interconnection.

  The Department of Hospital Therapy was established in 1933 on the initiative of Professor Nikolay Ivanovich Kornetov on the basis of the Republican Clinical Hospital, and was initially headed by Professor N. I. Kornetov. At that time, the need in the region for specialized medical and scientific institutions in the field of internal diseases was high, and the establishment of the department was one of the first serious steps in this direction. At the time of its founding, the department was designed for 80 beds, of which 20 belonged to the tropical diseases unit (L. M. Isayev), which constituted a sufficiently large clinical base for its era. Under the leadership of Professor N. I. Kornetov, the department's staff developed scientifically grounded methods for treating diseases specific to the climatic and geographical conditions of Central Asia, and this research later became the foundation for the formation of the regional pathology field.

  During that period, assistants M. A. Polyukhov, T. S. Mnaskanov, V. Lebedeva, Ye. A. Chivkunova, V. P. Kuznetsova, O. I. Novikova, A. N. Garanyan, and V. I. Garkusha worked at the department, along with graduate students N. A. Mirzoyan and Z. B. Abdukulova. Members of this team took an active part not only in clinical practice but also in the department's research work, teaching students, and mentoring young specialists, which was an important stage in the formation of the department's team.

  During the period when Professor N. I. Kornetov led the department, its staff successfully defended a number of candidate and doctoral dissertations. During this period, the department's clinical base was expanded, its material and technical resources were improved, and a number of accomplished scientific and pedagogical personnel were formed — including U. K. Vakhabova, B. Kh. Khamzaliyev, B. R. Rustamov, V. I. Garkusha, O. A. Lagutina, N. M. Mukharlamov, and N. R. Aralov. A number of other assistants and associate professors at the department also defended their doctoral dissertations (N. N. Kornetov, A. D. Jalolov, B. R. Rustamov, V. A. Jalolova, R. R. Sattarov, and N. R. Aralov). Among the department's scientific directions, issues of regional pathology have consistently held a leading place. Since 1933, the department has carried out multifaceted scientific and pedagogical activity: Professor N. Kornetov, Professor A. S. Mnushkin, and Professor V. Yu. Yoffe made significant contributions to the development of medical science. In shaping Samarkand State Medical Institute, and the Department of Hospital Therapy in particular, the scientific views and practical experience of Russian scientists M. P. Konchalovsky and M. Ya. Yarotsky were of great importance in their time. Over the years, the department has been led at various times by experienced scientists such as Professor B. Yu. Yoffe, Professor A. S. Mnushkin, Associate Professor D. A. Jalolov, Associate Professor O'. K. Vakhobova, Professor B. R. Rustamov, and Associate Professor V. A. Jalolova, which served to continuously strengthen the department's scientific and pedagogical potential.

  Doctor of Medical Sciences Aralov Nematilla Ravshanovich headed the Department of Hospital Therapy and Endocrinology from 2009 to 2020. In 1994, he successfully defended his candidate dissertation on "Clinical and Immunological Changes in Infection-Related Bronchial Asthma and Their Correction Using T-Activin," and in 2005 his doctoral dissertation on "Immunogenetic Mechanisms in the Pathogenesis of Chronic Obstructive Pulmonary Disease in Smokers and the Improvement of Its Treatment." His scientific research has been published in national and foreign scientific publications and leading scientific journals, and has been highly regarded by the European Respiratory Society (ERS) and the Euro-Asian Respiratory Society, earning him a number of state grants. He actively participated in scientific congresses and conferences held throughout the Republic of Uzbekistan, as well as in council meetings of societies of therapists and immunologists. N. R. Aralov, Doctor of Medical Sciences and a physician of the highest category, served as a member of the D.087.50.01 Specialized Scientific Council at the Sh. Alimov Named Specialized Scientific-Practical Medical Center for Phthisiology and Pulmonology.

  Among the notable scientists working in the field of internal diseases and hospital therapy at other leading medical institutions of our country, Doctor of Medical Sciences, Professor Ravshanbek Babajonovich Abdullayev, who served as Vice-Rector for Scientific Work and Innovation at Urgench State Medical Institute, holds a special place. He currently heads the Department of Internal Diseases, Rehabilitology, and Traditional Medicine, and carries out extensive scientific and practical work in the fields of internal diseases, gastroenterology, and therapy, and is the author of numerous scientific articles in these fields.

  From 2022 to the present, the 4th Department of Internal Diseases at Samarkand State Medical University has been headed by Ismailov Jamshid Abduraimovich. J. A. Ismailov defended his doctoral dissertation under the scientific supervision of Rizayev Jasur Alimdjanovich, Rector of Samarkand State Medical University, Doctor of Medical Sciences, Professor.