Биология ва тиббиёт муаммолари 2024 №4 (155)
Subject of the article
ДИАГНОСТИКА, ЛЕЧЕНИЕ И ПРОФИЛАКТИКА МЕТАСТАЗОВ В РЕГИОНАРНЫЕ ЛИМФОУЗЛЫ ШЕИ ПРИ РАКЕ ГОРТАНИ (155-158)
Authors
Насретдинова Махзуна Тахсиновна, Рахимов Жахонгир Хатамович, Улмасов Фирдавс Гайратович
Institution
Самаркандский государственный медицинский университет, Республика Узбекистан, г. Самарканд
Abstract
У 26,9% из 581 больного раком гортани развились регионарные метастазы. Трудности их диагностики обусловливают необходимость применения профилактических мер воздействия на очаги регионарного распространения метастазов. Из 147 пациентов с раком гортани II—III стадии (T2NOMO—T3NOMO) у 31 было проведено плановое облучение шейных лимфатических узлов, у 37 - профилактическая операция на шее, у 79 пациентов специальное лечение шейных лимфатических узлов не проводилось. Первичная опухоль была подвергнута комбинирован-ному, радиологическому или хирургическому лечению. Анализ 5- и 10-летней выживаемости не выявил какого-либо влияния профилактического лечения лимфатических узлов на общую выживаемость.
Key words
: рак гортани, метастазы, лимфатические узлы.
Literature
1. Rizaev J. A. et al. Peculiarities of the Dynamics of Morbidity of allergic Diseases among Children of Tashkent //Annals of the Romanian Society for Cell Biology. – 2021. – С. 15309-15319. 2. Rizaev J. A., Jumaev S., Rakhimova D. Influence of various treatment regimens on functional-oxidation dysfunction and hipoxy celle cutanea in patients with chronic obstructive pulmonary diseases and parodontitis //International Journal of Pharmaceutical Research. India. – 2020. – Т. 12. – С. 1276-1279. 3. Rizaev J. A., Ruzimurotova Y. S., Khaydarova G. A. THE IMPACT OF SOCIAL AND HEALTH FACTORS AT WORK AND AT HOME ON NURSES'HEALTH //Вестник магистратуры. – 2022. – №. 2-1 (125). – С. 10-12. 4. Rizaev J. A., Umirzakov Z. B. B., Umirov S. E. Ways to Optimize Medical Services for Covid-19 Patients //Specialusis Ugdymas. – 2022. – Т. 1. – №. 43. – С. 1217-1224. 5. Rizaev J. A., Sh A. M. COVID-19 VIEWS ON IMMUNOLOGICAL ASPECTS OF THE ORAL MUCOSA //European research: innovation in science, education and technology. – 2022. – С. 111-113. 6. Snyderman CH, Carrau RL, Kassam AB, Zanation A, Prevedello D, Gardner P et al. Endoscopic skull base surgery: principles of endonasal oncological surgery. J Surg Oncol 2008;97:658–64 7. Lund V, Stammberger H, Nicolai P, Castelnuovo P, Beal T, Beham A et al. European position paper on endoscopic management of the nose, paranasal sinuses and skull base. Rhinol Suppl 2010;22:1–144 8. Lund V, Wei W. Endoscopic resection of malignant sinonasal tumors: an eighteen year experience. Rhinology 2015;40:407–11 9. Nicolai P, Battaglia P, Bignami M, Bolzoni Villaret A, Delu G, Khrais T et al. Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10-year experience. Am J Rhinol 2008;22:308–16 10. Eloy J, Vivero R, Hoang K, Civantos FJ, Weed DT, Morcos JJ et al. Comparison of transnasal endoscopic and open craniofacial resection for malignant tumors of the anterior skull base. Laryngoscope 2009;119:834–40 11. Batra P, Luong A, Kanowitz SJ, Sade B, Lee J, Lanza DC et al. Outcomes of minimally invasive endoscopic resection of anterior skull base neoplasms. Laryngoscope 2010;120:9–16 12. Devaiah AK, Andreoli MT. Treatment of esthesioneuroblastoma: a 16-year meta-analysis of 361 patients. Laryngoscope 2009;119:1412–16 13. Rimmer J, Lund V, Beale T, Howard D, Wei W. Olfactory neuroblastoma – a 35 year experience and suggested follow-up protocol, Laryngoscope 2014;124:1542–49 14. Lund VJ, Chisholm EJ, Howard DJ, Wei WI. Sinonasal melanoma: a review of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resection. Rhinology 2012;50:203–10 15. Zanation A, Ferlito A, Rinaldo A, Gore M, Lund V, Mckinney K et al. When, how and why to treat the neck in patients with esthesioneuroblastoma: a review. Eur Arch ORL 2010;267:1667–71 16. Ang KK, Garden AS. Radiotherapy for Head and Neck Cancer: Indications and Techniques, 3rd edn. Lippincott, 2006 17. Shakhanova Sh. Sh., Rakhimov M. N. Aspects of sarcopenia syndrome in oncological practice: diagnosis and treatment (literature review) // Journal of Biomedicine and Practice. 2023, vol. 8, issue 3, pp. 406-417 18. Rakhimov M. N., Tulanov T. B., Shakhanova Sh. Sh., Aslsnova M. L. Pathogenetic aspects of cancer anorexia// Journal of Biomedicine and Practice. 2023, vol. 8, issue 4, pp.192-201 19. Dirix P, Vanstraelen B, Jorissen M, Vander Poorten V, Nuyts S. Intensity-modulated radiotherapy for sinonasal cancer: improved outcome compared to conventional radiotherapy. Int J Radiat Oncol Biol Phys 2010;78:998–1004 20. Shakhanova Sh. Sh., Rakhimov N. M., & Murodov Sh. T.. (2024). Aspects of sarcopenia syndrome in oncological practice: diagnosis and treatment. The American Journal of Medical Sciences and Pharmaceutical Research, 6(02), 16–25. 21. Bristol IJ, Ahamad A, Garden AS, Morrison WH, Hanna EY, Papadimitrakopoulou VA et al. Postoperative radiotherapy for maxillary sinus cancer: long term outcomes and toxicities of treatment. Int J Radiat Oncol Biol Phys 2007;68:719–30 22. Dulguerov P, Allal AS. Nasal and paranasal sinus car-cinoma: how can we continue to make progress? Curr Opin Otolaryngol Head Neck Surg 2006;14:67–72.