Biomeditsina va amaliyot jurnali, 2022 №6
Subject of the article
HYPERTENSIVE DISORDERS IN PATIENTS WITH GESTATIONAL DIABETES (431-438)
Authors
Atadjanova M. Muborak, Alieva A. Dilfuz
Institution
Republican Specialized Scientific and Practical Medical Center for Obstetrics and Gynecology
Abstract
306 pregnant women without carbohydrate metabolism disorders were examined at the Republican Screening Center at 11-13 weeks of pregnancy. Based on the results of the oral glucose tolerance test, 2 groups were formed: 1) 52 patients with gestational diabetes (main group), 2) 254 pregnant women without carbohydrate metabolism disorders (control group). When analyzing the impact on the development of GDM, hypertensive disorders in previous and current pregnancies came to the fore. Traditional risk indices (heredity, overweight, large fetus) were much less important. According to our data, hypertensive disorders are one of the main factors contributing to the development of gestational diabetes.
Key words
gestational diabetes mellitus, gestational hypertension, preeclampsia, risk markers.
Literature
Беттихер, О. А., И.Е. Зазерская, П.В. Попова, и др. Характеристика преэклампсии у беременных с гестационным диабетом // Журнал акушерства и женских болезней. – 2019. – № 5 (68). – С. 19-36. 2. Капустин, Р. В. Возможности прогнозирования и профилактики преэклампсии у беременных с сахарным диабетом. // Журнал акушерства и женских болезней. – 2018. – № 3 (67). – С. 20-29. 3. ACOG Practice Bulletin No. 190: Gestational Diabetes Mellitus. Obstetrics and gynecology. – 2018. – Vol. 2 (131). – P. e49-e64. 4. Billionnet C, Mitanchez D, Weill A, Nizard J, Alla F, Hartemann A, et al. Gestational diabetes and adverse perinatal outcomes from 716,152 births in France in 2012. Diabetologia. (2017) 60:636–44. doi: 10.1007/s00125-017-4206-6 5. Cosson E, Cussac-Pillegand C, Benbara A, Pharisien I, Nguyen MT, Chiheb S, et al. Pregnancy adverse outcomes related to pregravid body mass index and gestational weight gain, according to the presence or not of gestational diabetes mellitus: a retrospective observational study. Diabetes Metab. (2016) 42:38–46. doi: 10.1016/j.diabet.2015.06.001 6. Group HSCR, Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, et al. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med. (2008) 358:1991–2002. doi: 10.1056/NEJMoa0707943 7. Hiersch L, Berger H, Okby R, Ray JG, Geary M, McDonald SD, et al. Gestational diabetes mellitus is associated with adverse outcomes in twin pregnancies. Am J Obstet Gynecol. (2019) 220:102 e1–e8. doi: 10.1016/j.ajog.2018.10.027 8. Hod M, Kapur A, Sacks DA, et al. The International Federation of Gynecology and Obstetrics (FIGO) Initiative on gestational diabetes mellitus: A pragmatic guide for diagnosis, management, and care. Int J Gynecol Obstet. 2015;131:S173–S211. 9. International Society of Hypertension. Global Hypertension Practice Guidelines. Hypertension Vol 75, Issue 6, June 2020; Pages 1334-1357 10. Lai FY, Johnson JA, Dover D, Kaul P. Outcomes of singleton and twin pregnancies complicated by pre-existing diabetes and gestational diabetes: a population-based study in Alberta, Canada, 2005-11. J Diabetes. (2016) 8:45–55. doi: 10.1111/1753-0407.12255 11. Kosir Pogacnik R, Trojner Bregar A, Lucovnik M, Krajec M, Verdenik I, Blickstein I, et al. The effect of interaction between parity, gestational diabetes, and pregravid obesity on the incidence of preeclampsia. J Matern Fetal Neonatal Med. (2020) 33:931–4. doi: 10.1080/14767058.2018.1509311 12. Ovesen PG, Jensen DM, Damm P, Rasmussen S, Kesmodel US. Maternal and neonatal outcomes in pregnancies complicated by gestational diabetes. A nation-wide study. J Matern Fetal Neonatal Med. (2015) 28:1720– 4. doi: 10.3109/14767058.2014.966677 13. Salzer L, Tenenbaum-Gavish K, Hod M. Metabolic disorder of pregnancy (understanding pathophysiology of diabetes and preeclampsia). Best Pract Res Clin Obstet Gynaecol. 2015 Apr;29(3):328-38. 14. Weschenfelder F, Hein F, Lehmann T, Schleussner E, Groten T. Contributing factors to perinatal outcome in pregnancies with gestational diabeteswhat matters most? a retrospective analysis. J Clin Med. (2021) 10:348. doi: 10.3390/jcm10020348 15. Jasur Rizayev Alimjanovich, Larisa Rubenovna Agababyan, Anvar Ibragimovich Kamalov. Ayollarda tug‘ruqdan keyingi qon ketishlarni oldini olish va ularga qarshi kurashish bo‘yicha ko‘rsatilayotgan xizmatlar sifatining monitoringini tashkil etish// Oriental Renaissance: Innovative, educational, natural and social sciences Volume 1_ ISSUE 10, 2021 p. 166-169 16. Alimjanovich J. R., Agababyan L. R., Kamalov A. I. Prevention and Treatment of Postpartum Hemorrhage //CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES. – 2021. – Т. 2. – №. 4. – С. 204-209.