Журнал кардиореспираторных исследований 2023. №1

Тема статьи

SURUNKALI YURAK ISHEMIK KASALLIGI BO'LGAN BEMORLARDA NEYTROFILLAR DARAJASINING PERIODONT HOLATIGA BOG'LIQLIGI (9-13)

Авторы

Agababyan I.R., Kobilova N.A., Nurmatov O.S.

Учреждение

Самаркандский государственный медицинский университет

Аннотация

Yurak-qon tomir kasalliklarining asosiy sababi aterosklerozdir. Ateroskleroz - surunkali yallig'lanishli tomir kasalligi bo'lib, arteria devorida lipid pilakchalarning cho'kishiga olib keladi. Ushbu pilakchalarning to'planishi va rivojlanishi qon oqimini kamaytirishi mumkin, bu esa barcha organlar va to'qimalarning ishemiyasiga olib keladi, shuningdek, tromb shakllanishiga yordam beradi. Ateroskleroz bilan bog'liq bo'lgan asosiy yurak kasalliklariga miokard infarkti, o'tkir koronar sindrom, yurak etishmovchiligi, aritmiya va kardiyomiyopatiya kiradi. Dunyo bo'yicha yurakqon tomir kasalliklari birinchi o'rinni egallaydi va o'limning asosiy sababidir. Ateroskleroz surunkali yallig'lanish kasalligi bo'lganligi sababli, tadqiqotchilar boshqa yallig'lanish holatlari aterosklerozga hissa qo'shishi va kasallikning kechishini yomonlashtirishi mumkinligini tushunishga harakat qilishdi. Kam o'rganilgan yallig'lanish kasalliklaridan biri parodontit bo'lgan.. Ba'zi tadqiqotlarga ko'ra, har xil turdagi blyashka natijasida paydo bo'lgan periodontal kasallik (shu jumladan gingivit, AQShda 30 yosh va undan katta yoshdagi kattalar aholisining 47,2 foiziga ta'sir qiladi. 65 yoshdan keyin bu ko'rsatkich 70% gacha oshadi. Og'iz bo'shlig'ini parvarish qilish odatlaridan tashqari, periodontal kasallikka hissa qo'shadigan omillar orasida ijtimoiy-iqtisodiy holat, jins va chekish kiradi. Periodontit dunyoda barcha kasalliklar orasida oltinchi o'rinda turadi. Periodontit bilan birgalikda aterosklerozli bemorlarda yallig'lanishni saqlab qolishda muhim rol o'ynaydigan neytrofillarning roli haqidagi ushbu maqola o'rganilmagan muammolar pardasini biroz ochadi.

Ключевые слова

аterosklerotik yurak-qon tomir kasalliklari, periodontit, neytrofillar, yallig'lanishga qarshi sitokinlar, giperurikemiya.

Литературы

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