Doktor axborotnomasi 2024, №4 (116)


Subject of the article

HCV ETIOLOGIYALI JIGAR SIRROZIDA ANTIVIRUS TERAPIYA NEGIZIDA MIELOGRAMMA XUSUSIYATLARI (54-59)

Authors

N. F. Nuriddinova

Institution

Toshkent tibbiyot akademiyasi, Toshkent, O‘zbekiston

Abstract

Jahon sog‘liqni saqlash tashkilotining ma’lumotlariga ko‘ra, dunyoda taxminan 325 mln. odam parenteral gepa tit viruslari bilan zararlangan bo‘lib, 500 mln. dan ko‘p insonlar klinikasiz virus tashuvchanlikka ega. 2015 – yilda virusli gepatit tufayli 1,34 mln. o‘lim holati kuzatilgan. Gemostaz tizimi fiziologiyasi jigar faoliyati bilan bevosita bog‘liq, chunki gepatotsitlar ko‘plab koagulyatsion omillar, antikoagulyant oqsillar, fibrinoliz tizimi komponentlari va trombopoezni stimullovchi omillarni ishlab chiqaradi. Surunkali diffuz jigar kasalliklari bilan kasallangan bemorlarda qizilo‘ngach varikoz kengaygan venalaridan qon ketishi, gematomalar, gemorragik purpura, burun va milk qonashi, menorragiyalar kabi asoratlar kuzatilishi hozirgacha dolzarb klinik muammo bo‘lib qolmoqda. Maqsad: HCV eti ologiyali jigar sirrozida antivirus terapiya fonida mielogramma ko‘rsatkichlarining laborator diagnostikasini baholash. Ma’lumotlar 2020-2023 yillarda Toshkent tibbiyot akademiyasi 1-klinikasi gematologiya va gepatobiliar patologiyasi bo‘limlarida HCV etiologiyali surunkali gepatit bilan davolangan bemorlardan olindi.

Key words

jigar sirrozi, megakariotsit, suyak ko‘migi, trombotsit.

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