Биология ва тиббиёт муаммолари 2024 №4 (155)

Subject of the article

СТАРЕНИЕ КОЖИ: МОЛЕКУЛЯРНЫЕ МЕХАНИЗМЫ И СОВРЕМЕННЫЕ ПОДХОДЫ К АНТИВОЗРАСТНОЙ ТЕРАПИИ (430-439)

Authors

Сабиров Улугбек Юсупхонович, Ходжаева Нигора Бахромовна, Назарова Илона Игоревна

Institution

Республиканский специализированный научно-практический медицинский центр дерматовенерологии и космето-логии, Республика Узбекистан, г. Ташкент

Abstract

В статье приведены современные данные о роли клеточного старения в процессах старения и регенерации кожи, освещены патогенетические механизмы и гистологические аспекты клеточной сенесценции, обсуждена роль микровоспаления кожи и на-рушения локального иммунного ответа в процессе старения, а также рассмотрены современные методы диагностики и антивозрастной терапии, используемые в настоящее время и демонстрирующие высокую эффективность.

Key words

старение кожи; клеточная сенесценция; фибробласты; внеклеточный матрикс; матричная металлопротеиназа; микровоспаление; дермальное омоложение, антивозрастные методики.

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