Vol. 4 No. 2 (2023): JOURNAL OF CARDIORESPIRATORY RESEARCH
Subject of the article
EFFECTIVENESS OF INCLUDING GALAVIT IN THE COMPLEX THERAPY OF ACUTE PNEUMONIA CAUSED BY GRAM-NEGATIVE BACTERIA (52-55)
Authors
Ganiev A.G., Sanakulov
Institution
Andijan State Medical Institute
Abstract
Currently, infection with gram-negative bacteria becomes especially relevant in childhood, due to the increasing participation of the pathogen gram-negative bacteria, pneumonia, that is, atypical pneumonia (AP) in the development of not only acute inflammatory processes of the upper and lower respiratory tract, but also in some patients — in the formation of recurrent and chronic diseases of the respiratory system, through prolonged intracellular existence in the reticulohistiocytic system of the body and macrophages. In the observation of 90 children aged 4–14 years, the effectiveness of including the low molecular weight interferon inducer Galavita in the complex therapy of verified acute respiratory gram-negative pneumonia occurring on a aggravated premorbid background (respiratory allergy, bronchial asthma, frequent ARI) was shown to be effective. In those who received Galavit, the duration of the febrile period, intoxication, catarrhal syndrome in the nasopharynx and lungs, bronchial obstruction was reduced, and the immune status indicators improved.
Key words
gram-negative pneumonia, premorbid background, children, immunity, galavit
Literature
Абдуллаева З. А. и др. Сердечно-Сосудистые Осложнения На Фоне Перенесенного COVID-19 //Central Asian Journal of Medical and Natural Science. – 2022. – Т. 3. – №. 2. – С. 17-21. 2. Ташкенбаева Э. и др. Маркеры гиперурикемии как фактор риска и предикторы сердечно-сосудистых заболеваний //Журнал проблемы биологии и медицины. – 2016. – №. 2 (87). – С. 191-194. 3. Элламонов С. Н., Насырова З. А. КЛИНИЧЕСКИЕ И ИНСТРУМЕНТАЛЬНЫЕ ОСОБЕННОСТИ ТЕЧЕНИЯ ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА У БОЛЬНЫХ C КОМОРБИДНЫМИ СОСТОЯНИЯМИ //Журнал кардиореспираторных исследований. – 2022. – Т. 3. – №. 1. 4. Mayboroda Yu. N., Markina T. V., Uryaseva E. V. Evaluation of the effectiveness of the Galavit immunomodulator in the treatment of exacerbated catarrhal gingivitis // Medical Bulletin of the North Caucasus. No. 3 (27) 2012 5. Studentsov E. P., Ramsh S. M. et al. Adaptogens and related groups of drugs - 50 years of research / Reviews of clinical pharmacology and drug therapy / / Volume 11/2013/4 6. Gaynes R, Edwards JR (2015) Overview of nosocomial infections caused by gram-negative bacilli. Clin Infect Dis 41:848–854 Yfc`S^ ]ScW[acXdb[cSeac`nh[dd^XWaUS`[\¬ ɮ ɹɮɖɮɮɹ№2 | 2023 7. Ego A, Preizer JK, Vincent JL. Influence of diagnostic criteria on the incidence of ventilator-associated pneumonia. Breast. 2015; 147:347- 355. doi: 10.1378/l.14-0610. 8. Stevens JP, Kachniarts B, Wright SB, Gillis J, Thalmor D, Clardy P, et al. When the policy is right: variability in diagnoses of ventilatorassociated pneumonia in US hospitals. Crete Care Med. 2014;42:497–503. doi: 10.1097/CCM.0b013e3182a66903 9. Niederman M.S., Chastr J., Corkery K., Fink J.B., Lute S.E., Garcia M.S. BAY41-6551 achieves bactericidal concentrations of amikacin in tracheal aspirate from ventilated Gram-negative pneumonia patients. Intensive Care Med. 2012; 38:263–271. doi: 10.1007/s00134-011- 2420-0.