Doktor axborotnomasi 2024, №3 (115)
Maqola mavzusi
POST COVID SINDROMLARDA YURAK QON TOMIRLAR TIZIMIDAGI MORFOLOGIK VA MORFOMETRIK O‘ZGARISHLAR (40-44)
Mualliflar
Sh. Ya. Bustanov
Muassasa
Andijon davlat tibbiyot instituti, Andijon, Oʻzbekiston
Annotatsiya
Tadqiqotda post covid sindromidan turli yosh guruhida vafot etgan bemorlar autopsiya ma’lumotlarida miokard va toj tomirlarida yuzaga keladigan morofologik va morfometrik o‘zgarishlar o‘rganilgan. YuIKlarda yurak qon to mirlari tizimida sklerotik o‘zgarishlarni rivojlanishi, o‘tkazuvchanlikni va chap qorincha miokardining qisqaruvchan lik vazifasi buzilishiga, kardiomiostitlardagi distrofik o‘zgarishlariga, ularni morfometrik ko‘rsatkichlarini ya’ni kon traktil koeffistienti, to‘lqinsimon kechishli koeffistienti, dissostiastiya belgilari bo‘lgan kardiomiostitlarni miqdori va kardiomiostitlar diametrlarini ortishi bilan namoyon bo‘ldi.
Kalit so'zlar
COVID-19, SARS-CoV-2 virusi, post - COVID sindromi, yurak – qon tomir tizimi, YuIK, o‘tkir miokardit, miokard infarkti, toj tomirlari aterosklerozi.
Adabiyotlar
1. Абдуллаева З.А. и др. Сердечно-сосудистые осложнения на фоне перенесенного COVID-19. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES. Volume: 03 Issue: 02 | Mar-Apr 2022. С.17 21. ISSN: 2660-4159. http://cajmns. Central asian studies. org. 2. Иванников А.А., Эсауленко А.Н., Васильченко М.К., Алиджанова Х.Г., Петриков С.С. COVID-19 и сердеч но-сосудистая система. Часть II. Постковидный синдром. Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь». 2021;10(2):248-258. https://doi.org/10.23934/2223-9022-2021-10-2-248-25885. 3. Ларина В. Н., Головко М. Г., Ларин В. Г. Влияние коронавирусной инфекции (COVID-19) на сердечно сосудистую систему. ВЕСТНИК РГМУ | 2, 2020 | VESTNIKRGMU.RU. С 5-13. 4. Bermejo-Martin J.F., Almansa R., Torres A., González-Rivera M., Kelvin D.J. COVID-19 as a cardiovascular disease: the potential role of chronic endothelial dysfunction. Cardiovasc Res. 2020;116(10):e132–e133. PMID: 32420587 https://doi.org/10.1093/cvr/cvaa140]. 5. Chen C., Zhou Y., Wang D. W. SARS-CoV-2: a potential novel etiology of fulminant myocarditis // Herz. ‒ 2020. ‒ Vol. 45, № 3. ‒ P. 230‒232. DOI: 10.1007/s00059-020-04909-z. 6. Garg P., Arora U., Kumar A., Wig N. The “post-COVID” syndrome: how deep is the damage? J Med Virol. 2021;93(2):673–674. PMID: 32852801 https://doi.org/10.1002/jmv.26465. 7. Moreno-Pérez O., Merino E., Leon-Ramirez J.M., Andres M., Ramos J.M., Arenas-Jiménez J., et al. Post-acute COVID-19 syndrome. Incidence and risk factors: A Mediterranean cohort study. J Infect. 2021;82(3):378–383. PMID: 33450302 https://doi.org/10.1016/j.jinf.2021.01.004Russian Sklifosovsky Journal of Emergency Medical Care. 2021;10(2):248–258. https://doi.org/10.23934/2223-9022-2021-10-2-248-258. 8. Poredos P., Jezovnik M.K. Endothelial dysfunction and venous thrombosis. Angiology. 2018;69(7):564 567.https://doi.org/10.1177/ 000331971773223. 9. Sardu C., Gambardella J., Morelli M.B., Wang X., Marfella R., Santulli G. ypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence. J. Clin Med. 2020;9 (5):1417. PMID: 32403217 https://doi.org/10.3390/jcm9051417. 10. Schmieder R.E. Endothelial dysfunction: how can one intervene at the beginning of the cardiovascular continuum. J. Hypertens Suppl. 2006; 24(2):S31–35. PMID: 16601559 https://doi.org/10.1097/01.hjh.0000220101.57896.cd. 11. Simmonds P., Williams S., Harvala H. Understanding the outcomes of COVID-19—does the current model of an acute respiratory infection really fit. The Journal of General Virology.2021;102(3):001545. https:// doi.org/10.1099/jgv.0.001545.