Биология ва тиббиёт муаммолари 2024 №4 (155)

Maqola mavzusi

УРҒОЧИ КАЛАМУШЛАРНИНГ ДИЭСТРУС ДАВРИДА 10 ДАҚИҚАЛИ КЛИНИК ЎЛИМДАН КЕЙИНГИ ПОСТРЕАНИМАЦИОН ДАВРДА ВЕГЕТАТИВ НЕРВ ТИЗИМИ, ПРООКСИДАНТ, АНТИОКСИДАНТ ТИЗИМЛАРИ, ЭНДОГЕН ИНТОКСИКАЦИЯ, ҲАМДА РЕПРОДУКТИВ ТИЗИМ ГОРМОНАЛ КЎРСАТКИЧЛАРИДА ЎЗГАРИШЛАР (316-319)

Mualliflar

Кулиев Озоджон Абдирахмонович, Карабаев Аминжон Гадаевич

Muassasa

Самарқанд давлат тиббиёт университети, Ўзбекистон Республикаси, Самарқанд ш.

Annotatsiya

Диэструс даврида 10 дақиқали клиник ўлим ўтказган каламушларнинг постреанимацион даврининг биринчи кунидан бошлаб 21-кунгача симпатик нерв тизимининг устунлиги остида қонда ФСГ вa ЛГ эстрадиол гормонини миқдорини ортиши остида ҳимоя мослашув реакцияси таъминланган. 2. Постреаниматсион даврнинг 21- кунинг келиб, репродуктив тизимида гормонлар синтизини пасайиб боришида прооксидант тизимининг устунлиги эндоген интоксикация кўрсаткичларини юқори даражада сақланиши ва оқсилни чидамлик коэффициентини пасайиш ўрни аниқланди.

Kalit so'zlar

Вегетатив асаб тизими, МДА, каталаза, МСМ254, МСМ280 ФСГ, ЛГ, эстрадиол, прогестерон.

Adabiyotlar

1. Ariza Traslavisa G.A., Franci C.R. The CRH-R1 receptor mediates luteinizing hormone, prolactin, corticosterone and progesterone secretion induced by restraint sAyata C., Ropper A.H. Ischaemic brain oedema // J. Clin. Neurosci. 2011.- V.9. N2.-P. 113-124. 2. Arteaga Cabeza O., et al Neuroprotective effects of a dendrimer-based glutamate carboxypeptidase inhibitor on superoxide dismutase transgenic mice after neonatal hypoxic-ischemic brain injury. Neurobiol Dis. 2021 Jan;148:105201. 3. Arutyunyan, A.V. Vozrastnыe narusheniya gipotalamicheskoy regulyasii reproduktivnыx siklov i ix korreksiya / A.V.Arutyunyan, A.V.Korenevskiy // Uspexi gerontologii. – 2014. – T. 27, №2. – S. 275-283. (in Russ). 4. Avrushenko M.SH., Ostrova I.V. Postreanimasionnie izmeneniya ekspressii mozgovogo neyrotroficheskogo faktora (BDNF): vzaimosvyazъ s prosessom gibeli neyronov//. Obshaya reanimatologiya. 2017;13(4).-S.6-21. 5. Baranova T.YU. Funksionalnaya morfologiya gipotalamo-gipofizarno- nadpochechnikovoy sistemы pri ostrom infarkte miokarda: avtoref. dis. kand. med. nauk. M. – 2018. - 22 s. 6. Friptu V.G., Moldovanu I.V., Mazur I.A. Vzaimosvyazъ siklicheskix izmeneniy polovix gormonov i vegetativnix narusheniy v razvitii predmenstrualъnix simptomov. Rossiyskiy vestnik akushera-ginekologa. 2015;15(6):24-29. (in Russ). 7. Gabrielyan I.I., Leviskiy E.R., Dmitriev A.A. i dr. Skriningoviy metod opredeleniya srednix molekul v biologicheskix jidkostyax: Metod, rekomendasii. - Moskva, 1985. - 18 s. (in Russ). 8. Karabaev A.G. et al. Reactivity of the supraoptic, arcuate nucleus of the hypothalamus and the B-and D-basophilic cells of the adenohypophysis in the ear-ly postreanimation period. //European Journal of Mo-lecular & Clinical Medicine. 2021;8 (3): 954-957. Karabaev A.G. Relationship between the reactivi-ty of the autonomic nervous system and the morphofunctional activity of basophilic cells of the adenohypophysis in the post-resuscitation period. // Science and World International scientific journal 2020; 3 (79):55-62. 9. Karabaev A.G. et al. Reactivity of the supraoptic, arcuate nucleus of the hypothalamus and the B-and D-basophilic cells of the adenohypophysis in the early postreanimation period. //European Journal of Molecular & Clinical Medicine. 2021;8 (3), 954-957. (in Uzb). 10. Karabaev A.G. Morfofunksionalnыe izmeneniya GGNS v protsesse umiraniya i ojivleniya organizma. Dissert. na soisk. uchen. stepeni kand. med. nauk., Tashkent,1999(in Uzb). 11. Karabaev A.G. Relationship between the reactivity of the autonomic nervous system and the morphofunctional activity of basophilic cells of the adenohypophysis in the post-resuscitation period. // Science and World International scientific journal 2020; 3 (79),55-62. (in Uzb). 12. Karabayev A. G., R. I. Isroilov. Morphofunctional Changes in Basophilic Cells of the denohypophysis during Post-resuscitation Disease // Journal of Ad-vances in Medicine and Medical Research 2020;32 (8):130-135. 13. Rizaev J. A., Khaidarov N. K., Abdullaev S. Y. Current approach to the diagnosis and treatment of glossalgia (literature review) //World Bulletin of Public Health. – 2021. – Т. 4. – С. 96-98. 14. Rizaev J. A., Maeda H., Khramova N. V. Plastic surgery for the defects in maxillofacial region after surgical resection of benign tumors //Annals of Cancer Research and Therapy. – 2019. – Т. 27. – №. 1. – С. 22-23. 15. Rizaev J. A., Khazratov A. I., Iordanishvili A. K. Morphofunctional characteristics of the mucous membrane of the masticatory apparatus in experimental carcinogenesis //Russian Journal of Dentistry. – 2021. – Т. 25. – №. 3. – С. 225-231. 16. Negovskiy V.A., Moroz V.V. Teoreticheskie i klinicheskie problemi reanimatologii // Jurn.anesteziologiya i reanimatologiya, 2000, №6.-S..4 - 6. 17. Neyfelъd I.V., et al Rolъ estrogenov v vegetativnoy regulyasii serdechno-sosudistoy sistemi v menopauze // Mediko-farmasevticheskiy jurnal "Pulъs". 2021. Vol. 23. № 6.S.167-173. (in Russ). 18. Orlov YU.P., Lukach V.N., Dolgix V.T. i dr. Patogeneticheskaya znachi-most narushennogo obmena jeleza v formirovanii mikrotsirkulyatornыx rasstroystv pri reperfuzii (eksperimentalnoe issledovanie).// Sibirskiy meditsinskiy jurnal, 2012, № 5.-S.71-74. (in Russ). 19. Ostrova I. V., Avruщenko M. SH., Volkov A. V., Zarjetskiy YU. V. Polovыe razlichiya strukturnыx izmeneniy golovnogo mozga v postreanimatsionnom periode. Obщaya reanimatologiya. 2009; 5 (6) .-S. 60-65. 20. Polenov A.L. Gipotalamicheskaya neyrosekresiya // izd. "Nauka" 1993.- 89s. (in Russ). 21. Popkov V.M., CHesnokova N.P., Morrison V.V. i dr. Tipovыe patologicheskie protsessы, kak osnova patogeneza bolezney razlichnoy etiologii. Pod obщ. red. V.M. Popkova, N.P. CHesnokovoy. - Monografiya. - Saratov: Saratovskiy gosudarstvennыy meditsinskiy universitet im. V.I. Razumovskogo, 2017. - 540 s. 22. Samoylov M.O., Rыbnikova E.A. Molekulyarno-kletochnыe i gormonalnыe mexanizmы indutsirovannoy tolerantnosti mozga k ekstremalnыm faktoram sredы// Ros. fiziol. j. im. I.M.Sechenova. -2012. -T. 98. № 1, -S. 108-126. 23. Semchenko V.V., Stepanov S.S., Bogolepov N.N. Sinapticheskaya pla-stichnost golovnogo mozga (fundamentalnыe i prikladnыe aspektы). //Jurnal: Jurnal nevrologii i psixiatrii 2015;115(6) .-S. 115-115. 24. Stalъnaya I.D., Garishvili T.G. Opredelenie MDA. // sovremennie metodi v bioximii. Moskva,1977.- S. 66-68. 25. Stroev S.A., Samoylov M.O.//Endogennыe antioksidantы i gipoksicheskaya tolerantnost mozga. SPb.: In-t fiziologii im. I. P. Pavlova RAN, -2007.- 145s. 26. Veyna A.M. Zabolevaniya vegetativnoy nervnoy sistemы. izd. Moskva, Meditsina, 1991, - 616 s. (in Russ). 27. Volkov A. V., Zarjeskiy YU. V. Vliyanie immunomodulyatorov na postreanimasionnie izmeneniya v organizme (eksperimentalъnoe issledovanie). Tez. dokl. 12 go sъezda federasii anesteziologov ireanimatologov 19-22 sentyabrya 2010 g. Moskva. M.; 2010.-S. 97-98. 28. Volkov A.V., Moroz V.V., Ejova K.N., Zarjeskiy YU.V. Rolъ polovix steroidov v vosstanovitelъnom periode posle klinicheskoy smerti (eksperimentalъnoe issledovanie). Obshaya reanimatologiya. 2010;4(1):-S.1-18. (in Russ). 29. Yаkimov I. A, Loginova E. S. Analiz izmeneniy urovnya gormonov щi-tovidnoy jelezы pri nekotorыx vidax smerti//Jurn: Almanax sovremen-noy nauki i obrazovaniya, 2017. № 6 .- S.91-92 30. Zarechnova N.N., Slыnko T.N. Morfofunksionalnaya perestroyka nekotorыx organov u jivotnыx v protsesse gornoy adaptatsii i dedaptatsii. V kn. Nauchno-innovatsionnaya deyatelnost KRSU. Bishkek, 2011. -S. 59–67. (in Russ). 31. Zarjetskiy YU.V., Volkov A.V. Nekotorыe voprosы patogeneza i terapii terminalnыx i postreanimatsionnыx sostoyaniy (eksperimentalnыe issledovaniya). // Obщaya reanimatologiya. 2012. №8 (4).- S.55-68. (in Russ).