Биология ва тиббиёт муаммолари 2024 №4 (155)


Maqola mavzusi

WAYS TO IMPROVE THE RESULTS OF SURGICAL TREATMENT OF HEPATIC ECHINOCOCCOSIS AND PREVENTION OF RECURRENCE (194-196)

Mualliflar

Rakhmanov Kosim Erdanovich, Davlatov Salim Sulaymonovich, Radjabov Jasur Pardabayevich

Muassasa

1 - Samarkand State Medical University, Republic of Uzbekistan, Samarkand; 2 - Bukhara State Medical Institute, Republic of Uzbekistan, Bukhara

Annotatsiya

The clinical study included 371 patients with liver echinococcosis. Optimization of the tactics of surgical treatment of liver echinococcosis, taking into account the choice of access, method of treatment and elimination of the residual cavity, as well as correction of the course of prophylactic chemotherapy, improved the quality of care by reducing the frequency of immediate postoperative complications from 12.5% to 4.3% and the recurrence of the disease from 11.9% to 2.6%. It is clinically justified to correct the dose of albendazole for the prevention of recurrence of liver echinococcosis in patients with concomitant chronic diffuse liver pathology, which made it possible to reduce the likelihood of adverse reactions from 52.7% to 18.3%, and, accordingly, indicators of hepatic aminotransferases: ALT in the comparison group from 1.14± 0.11 to 0.62±0.05 mmol/l in the main group and AST from 0.72±0.07 to 0.52±0.04 mmol/l.

Kalit so'zlar

liver echinococcosis, surgical treatment, chemotherapy.

Adabiyotlar

1. Ризаев Ж. А. и др. Выбор хирургической тактики в зависимости от дооперационной топической диагностики эхинококкоза печени // Биология ва тиббиёт муаммолари. – 2021. – Т. 5. – №. 131. – С. 117-119. 1. Ризаев Ж. А. и др. Оптимизация диагностики раз-личных морфологических форм эхинококкоза печени // Биология ва тиббиёт муаммолари. – 2021. – Т. 5. – №. 131. – С. 120-124. 2. Antepli̇oğlu T. et al. Assessment of oxidative stress and tissue damage in Echinococcus granulosus naturally in-fected bovine liver //Tissue and Cell. – 2024. – Т. 87. – С. 102333. 3. Nazyrov F. G. et al. Шляхи покращення результатів хірургічного лікування ехінококкоза печінки //Неонатологія, хірургія та перинатальна медицина. – 2018. – Т. 8. – №. 3 (29). – С. 39-43. 4. Rakhmanov K. E., Davlatov S. S., Abduraxmanov D. S. H. Correction of albendazole disease after echinococcectomy of the liver //International Journal of Pharmaceutical Research (09752366). – 2020. – Т. 12. – №. 3. 5. Shamsiev A. M. et al. Differentiated treatment tactics in surgery of liver echinococcosis //Experimental and Clin-ical Gastroenterology. – 2020. – Т. 174. – №. 5. – С. 72-77. 6. Shamsiev A. M. et al. Эхинококкоз печени: частота встречаемости, патогенез, классификация, диагностика и лечение (обзор литературы) //Клінічна та експериментальна патологія. – 2018. – Т. 17. – №. 3. 7. Shamsiyev A. M. et al. Development of surgical treat-ment of echinococcosis of the liver (literature review) // Modern innovations: current directions of scientific re-search. – 2017. – С. 45-49. 8. Zarifovich K. B. et al. Лазерная фотодинамическая терапия как метод обработки остаточной полости по-сле эхинококкэктомии печени //Journal of biomedicine and practice. – 2022. – Т. 7. – №. 4. 9. Zhu J. et al. Ghrelin regulating liver activity and its potential effects on liver fibrosis and Echinococcosis //Frontiers in Cellular and Infection Microbiology. – 2024. – Т. 13. – С. 1324134.