Журнал кардиореспираторных исследований 2024. №1

Maqola mavzusi

CLINICAL AND PROGNOSTIC VALUE RENAL DYSFUNCTION IN PATIENTS WITH CORONARY HEART DISEASE (23-26)

Mualliflar

Tashkenbaeva Eleonora Negmatovna, Pulatova Parizoda Khamzaevna

Muassasa

Самаркандский государственный медицинский университет

Annotatsiya

Heart and vascular diseases are the leading cause of mortality in industrialized countries [1]. For adequate assessment, treatment and prevention of cardiovascular diseases, high-quality and accurate diagnostics, including visualization of the heart and blood vessels, are of great importance. Intravenous or intraarterial administration of radiocontrast agents allows you to accurately determine the anatomy of blood vessels, the nature and location of lesions in them, and evaluate the characteristics of the blood supply to various organs and tissues. Without such information, modern treatment would simply be impossible. Selective angiography and computed tomography with the introduction of contrast agents are used everywhere in practical medicine. Therefore, safety issues for a study or intervention using KB become important. Despite the significant progress made in the development of KBs, they have a number of adverse effects, incl. nephrotoxicity. Prevention of nephrotoxic effects of KB, so-called. contrast-induced nephropathy remains an urgent problem, since it is known that CIN is often a harbinger of chronic renal failure, which worsens the prognosis [6]. Active use of X-ray computed tomography with intravenous administration of KB at the diagnostic stage increases not only the total radiation dose, but also nephrotoxicity.

Kalit so'zlar

Key words: coronary heart disease, radiocontrast agents, coronary angiography, nephrotoxicity, contrast-induced nephropathy, chronic kidney disease

Adabiyotlar

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