Биология ва тиббиёт муаммолари 2024 №2 (152)
Maqola mavzusi
CHARACTERISTICS OF THE CLINICAL COURSE OF COVID-19 INFECTION ON THE BACKGROUND OF BRONCHIAL ASTHMA IN CHILDREN (194-196)
Mualliflar
Khalmatova Barno Turdikhodjayevna, Abdujalilova Maftuna Shukhrat kizi, Khoshimov Abrorjon Anvarjonovich
Muassasa
1 - Kimyo International University in Tashkent, Republic of Uzbekistan, Tashkent; 2 – Tashkent Medical Academy, Republic of Uzbekistan, Tashkent
Annotatsiya
Purpose of the study. Determination of the features of the clinical course of COVID-19 infection against the background of bronchial asthma in children. Materials and methods of research. 51 sick children aged 7 to 18 years who had suffered a corona viral infection were under observation. The control group consisted of 35 children of the same age. Results. The main difference in the clinical picture of corona virus infection in children of the main group was that in children of the first group a dry, painful cough predominated, and in children of the second group - loss of smell and low-grade body temperature. Conclusion. Patients in the main group experienced asthma attacks during the coronavirus infection, but in children who regularly took medications for asthma, there was no worsening of their condition due to the addition of the coronavirus.
Kalit so'zlar
children, bronchial asthma, corona virus infection.
Adabiyotlar
1. Геппе Н.А., Колосова Н.Г. и др., COVID-19 у детей с бронхиальной астмой: клинические проявления, варианты течения, подходы к терапии// Иммунология. 2021; 42(3): 254-260. 2. Левина Ю.Г., Намазова-Баранова Л.С. и др. Особенности течения бронхиальной астмы и респираторной заболеваемости у детей в период пандемии COVID-19: результаты ретроспективного сравнительного наблюдательного исследования // Вестник РАМН. 2020;75(5S):455–464. 3. COVID-19 confirmed cases and deaths. The United Nations Children’s Fund (UNICEF). Accessed June 28th, 2022. 4. Hou H., et all. Magnesium acts as a second messenger in the regulation of NMDA receptor-mediated CREB signaling in neurons // Mol. Neurobiol. 57.-2020.-2539–2550. 5. Hou Y.J., Okuda K. et al. SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract// Cell 2020.182:429-46.e14. 6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China// Lancet. 2020 Feb 15.395(10223):497-506. 7. Parri N., Lenge M. et all. Coronavirus Infection in Pediatric Emergency Departments (CONFIDENCE) Research Group. Children with COVID-19 in pediatric emergency departments in Italy. N. Engl//J. Med. 2020;383(2):187-90. 8. Wee L.E., Conceicao EP, Tan JY, Sim JXY, Venkatachalam I. Reduction in asthma admissions during the COVID-19 pandemic: consequence of public health measures in Singapore// European Respiratory Journal 2021.-57:2004493; World Health Organization. WHO coronavirus (COVID-19) dashboard. Accessed September 20, 2021. https://covid19.who.int