Biomeditsina va amaliyot jurnali, 2022 №5

Maqola mavzusi

THE ROLE OF THE MICROELEMENT ZINC IN THE PROCESS OF METABOLISM (LITERATURE REVIEW) (378-383)

Mualliflar

Allaeva Munira Jurakulovna, Boboev Bekhzod Mominjon ogli,

Muassasa

Tashkent Medical Academy

Annotatsiya

This review of the literature analyzes the available scientific studies on the role of zinc in the body, as well as the mechanisms of action and its significance in the pathogenesis of obesity. In experimental studies, it was found that the zinc content decreases in adipose tissue in obesity and affects the activity and differentiation of adipocyte cells. Considering zinc as one of the regulators of adipogenesis, a violation of its metabolism is observed along with dysfunction of adipose tissue. By correcting the exchange of zinc in adipose tissue, it is possible to achieve normalization of the exchange of the lipid spectrum. At the same time, since its excessive accumulation in adipocytes also leads to their dysfunction, it is important to conduct additional studies to study the mechanisms of action of zinc deficiency and excess in adipose tissue.

Kalit so'zlar

zinc; adipose tissue; adipogenesis; atherosclerosis; zinc-α2-glycoprotein.

Adabiyotlar

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