Kardiorespirator tadqiqotlar jurnali 2022, No SI-4.1

Тема статьи

NEUROPEPTIDE-CYTOKINE STATUS IN CHRONIC ISCHEMIC HEART DISEASE (65-69)

Авторы

Khusainova M.A.

Учреждение

Samarkand State Medical University

Аннотация

The spread of metabolic syndrome (MS) in developed countries, which, according to WHO experts, assumed the nature of a pandemic in the XXI century, contributes to the increase in the incidence of coronary heart disease (CHD). MS is currently considered a kind of cluster of risk factors for atherosclerosis, Coronary heart disease and type 2 diabetes mellitus. Since the main diagnostic sign of MS is abdominal type of obesity, it is natural to assume that if it is present, certain clinical and pathogenetic features should be revealed in patients with coronary heart disease. By a well - known analogy with phenotypes Currently, chronic obstructive pulmonary disease can be considered a special phenotype of coronary heart disease against the background of abdominal obesity. A decrease in the production of endorphins is accompanied by an increase in the activity of the sympathetic system, an increase in the production of cortisol by the adrenal glands, stimulation of gluconeogenesis, increased synthesis of triacylglycerols and lipogenesis, which creates conditions for the potentiation of atherogenesis.

Ключевые слова

ischemic disease, atherosclerosis, anxiety, depression, beta-endorphin, cytokines

Литературы

Абдувакилов Ж., Ризаев Ж. Биохимические маркеры соединительной ткани у больных хроническим воспалительным пародонтитом на фоне метаболического синдрома //Stomatologiya. – 2018. – Т. 1. – №. 1 (70). – С. 11-14. 2. Alisherovna, K. M., & Xudoyberdiyevich, G. X. FEATURES OF HEART DAMAGE IN PATIENTS WITH VIRAL CIRRHOSIS OF THE LIVER. Alisherovna, K. M., & Xudoyberdiyevich, G. X. FEATURES OF HEART DAMAGE IN PATIENTS WITH VIRAL CIRRHOSIS OF THE LIVER. 3. Alisherovna, K. M., Erkinovna, K. Z., Jamshedovna, K. D., & Toshtemirovna, E. M. M. (2022). STUDY OF QUALITYOF LIFE INDICATORS IN PATIENTS WITH CORONARY HEART DISEASE USING THE SF-36 QUESTIONNAIRE. Web of Scientist: International Scientific Research Journal, 3(5), 558-564. 4. Alisherovna, K. M., Tatlibayevich, Y. S., Toshtemirovna, E. M. M., & Nizamitdinovich, H. S. (2021). Diagnostic Significance Daily Monitoring of Blood Pressure in Young Women (Under 40 Years Old) with Arterial Hypertension. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, 2(5), 461-465. 5. Buribayevich, N. M. (2022). Treatment of Chronic Heart Failure in Patients with Type 2 Diabetes Mellitus. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, 3(1), 183-186. 6. Erkinovna, K. Z., Davranovna, M. K., Toshtemirovna, E. M. M., & Xudoyberdiyevich, G. X. (2022). CORRECTION OF COMPLICATIONS IN CHRONIC HEART FAILURE DEPENDING ON THE FUNCTIONAL STATE OF THE KIDNEYS. Web of Scientist: International Scientific Research Journal, 3(5), 565-575. 7. Makhmudova, K. D., & Gaffarov, H. H. (2021, February). STUDYING THE LIVER FUNCTION IN BURN RECONVALESCENTS. In Archive of Conferences (Vol. 15, No. 1, pp. 208-210). 8. Toshtemirovna, E. M. M., Alisherovna, K. M., Totlibayevich, Y. S., & Muxtorovna, E. M. (2022). HEARTS IN RHEUMATOID ARTHRITIS: THE RELATIONSHIP WITH IMMUNOLOGICAL DISORDERS. Spectrum Journal of Innovation, Reforms and Development, 4, 34-41. 9. Toshtemirovna, E. M. M., Alisherovna, K. M., Totlibayevich, Y. S., & Duskobilovich, B. S. (2022). THE VALUE OF XANTHINE IN CHRONIC HEART FAILURE. Spectrum Journal of Innovation, Reforms and Development, 4, 24-29. 10. Toshtemirovna, E. M. M., Nizamitdinovich, K. S., Tadjiyevich, X. A., & Xudoyberdiyevich, G. X. (2022). ASSESSMENT OF RENAL DYSFUNCTION IN PATIENTS WITH CHRONIC HEART FAILURE. 11. Xaydarov, S. N., & Normatov, M. B. (2021). DETERMINATION OF IRON DEFICIENCY ANEMIA AT THE PREGNANCY PERIOD. Scientific progress, 2(4), 325-327. 12. Ziyadullaev S. et al. The effect of budesonide on the quality of life in patients with bronchial asthma //European Journal of Molecular & Clinical Medicine. – 2020. – Т. 7. – №. 2. – С. 1760-1766. 13. Yarmatov, S. T. (2021). YURAK ISHEMIK KASALLIGI VA BACHADON MIOMASI BO'LGAN BEMORLARNI DAVOLASHDA ANTIKOUGULYANT VA ANTITROMBOSITAR TERAPIYANI O’TKAZISH BO’YICHA KLINIK KUZATUVNI OLIB BORISH. Scientific progress, 2(3), 792-797. Yarmukhamedova, S. (2020). SURUNKALI GLOMERULONEFRIT BILAN OG ‘RIGAN BEMORLARDA ARTERIAL QON BOSIMINING SUTKALIK MONITORING KO ‘RSATKICHLARINI BAXOLASH. Журнал кардиореспираторных исследований, 1(1), 103-108. 15. Норматов, М. Б. (2022). EFFICACY OF AMLODIPINE IN ARTERIAL HYPERTENSION COMBINED WITH TYPE 2 DIABETES MELLITUS. Журнал кардиореспираторных исследований, 3(1). 16. Хайдарова, З. (2021). ЭНТРОПИЯ И НАРУШЕНИЯ СЕРДЕЧНОГО РИТМА У БОЛЬНЫХ, ПЕРЕНЕСШИХ ИНФАРКТ МИОКАРДА. Журнал кардиореспираторных исследований, 2(4), 59-62. 17. ШОДИКУЛОВА, Г. З., ЭРГАШОВА, М. М., КУРБАНОВА, З. П., & УМАРОВ, И. Д. (2022). REVMATOID ARTRIT VA IKKILAMCHI OSTEOARTROZ BILAN KASALLANGAN AYOLLARDA KARDIOVASKULYAR XAVFINI BAHOLASH. ЖУРНАЛ БИОМЕДИЦИНЫ И ПРАКТИКИ, 7(1). 18. Эргашова, М. М., & Шодикулова, Г. З. (2021). РЕВМАТОИД АРТРИТ ВА ИККИЛАМЧИ ОСТЕОАРТРОЗ КАСАЛЛИГИ БОР БЕМОРЛАРДА ЮРАК ГЕМОДИНАМИКАСИНИНГ ЎЗИГА ХОС ХУСУСИЯТЛАРИ. ЖУРНАЛ БИОМЕДИЦИНЫ И ПРАКТИКИ, 6(1). 19. Ярмухаммедова, С. (2020). ОЦЕНКА ПРИЗНАКОВ ДИАСТОЛИЧЕСКОЙ ДИСФУНКЦИИ ПРАВОГО ЖЕЛУДОЧКА У БОЛЬНЫХ С АРТЕРИАЛЬНОЙ ГИПЕРТОНИЕЙ. Журнал кардиореспираторных исследований, 1(2), 88-92. 20. Ярмухаммедова, С., Гаффоров, Х., & Ярматов, С. (2020). JIGAR SIRROZIDA YURAKNING SISTOLIK VA DIASTOLIK DISFUNKTSIYASINING AHAMIYATI. Журнал кардиореспираторных исследований, 1(2), 85-87.