Биология ва тиббиёт муаммолари 2024 №5 (156)

Тема статьи

FEATURES OF BRONCHIAL ASTHMA IN CHILDREN WITH CONSEQUENCES OF PERINATAL CENTRAL NERVOUS SYSTEM LESIONS (162-166)

Авторы

Khaydarova Sarvinoz Khaydarjonovna, Mavlyanova Zilola Farkhadovna, Sharipov Rustam Khaitovich, Ashurov Rustamjon Furkatovich, Shamsiddinova Madinabonu Shukhrat kizi

Учреждение

Samarkand State Medical University, Republic of Uzbekistan, Samarkand

Аннотация

Objective: The study aimed to analyze the effects of perinatal central nervous system (CNS) damage on the course of bronchial asthma in children. Materials and Methods: To assess the influence of perinatal CNS damage on the progression of bronchial asthma in children, a total of 103 patients with moderate bronchial asthma, aged 5 to 7 years (70 boys and 33 girls), were examined. The children were divided into two groups: the main group, which included 72 children (51 boys and 21 girls) with asthma and long-term consequences of perinatal CNS damage, and the comparison group, consisting of 31 children (19 boys and 12 girls) with asthma but without neurological impairments. Results: Based on the collected data, it was found that perinatal CNS damage significantly affects the further development and course of bronchial asthma in children. Specifically, bronchial obstructive syndrome, as a potential initial manifestation of asthma, begins earlier in children with a burdened medical history and neurological symptoms. In the main group, the peak incidence occurred in the first year of life, whereas in the comparison group, it was between 2 and 3 years of age. Furthermore, the first episode of bronchial obstructive syndrome in the main group contributed to recurrent asthma symptoms as early as the first year of life, with children in this group experiencing 3-4 to 7 episodes of bronchial obstructive syndrome before the diagnosis of bronchial asthma, compared to 2-4 episodes in the comparison group.

Ключевые слова

bronchial asthma, consequences, perinatal damage, central nervous system, bronchial obstructive syndrome, neurological symptoms.

Литературы

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