Биология ва тиббиёт муаммолари 2024 №4 (155)

Тема статьи

PROGNOSTIC SIGNIFICANCE OF HYPERURECEMIA IN THE DEVELOPMENT OF CHRONIC KIDNEY DISEASE (459-462)

Авторы

Tashkenbayeva Eleonora Negmatovna, Esankulov Mukhammad Olimovich

Учреждение

Samarkand State Medical University, Republic of Uzbekistan, Samarkand

Аннотация

A review of the literature is presented highlighting the role of hyperuricemia as a risk factor for the development of chronic kidney disease and one of the factors in the progression of existing kidney disease. Epidemiological information on the relationship between hyperuricemia and kidney damage is provided. The mechanisms of the damaging effect of uric acid on renal tissue, obtained in experiments and clinical conditions, are considered. The main directions of correction of hyperuricemia and the place of this therapy in the general strategy of nephroprotection have been deter-mined.

Ключевые слова

hyperuricemia, gout, chronic kidney disease, tubulointerstitial fibrosis.

Литературы

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