Doktor axborotnomasi 2022, №2.2 (104)

Тема статьи

CLINICAL AND ANAMNESTIC FEATURES OF PATIENTS WITH ENDOMETRIAL POLYPS AND INFERTILITY (43-47)

Авторы

Yu. M. Tilavova, B. B. Negmadjanov, G. T. Rabbimova, V. O. Kim

Учреждение

Samarkand state medical university, Samarkand, Uzbekistan

Аннотация

Clinical and anamnestic features of 45 patients were studied with hysteroscopic and histologically confirmed diagnosis of endometrial polyp and women without intrauterine pathology. All patients were of reproductive age from 20 to 45 years. The average age of the surveyed was 32 years, BMI 28 kg/m2, the characteristics of menstrual func-tion, the frequency of obstetric and gynaecological surgical interventions and past gynaecological diseases were de-scribed. The clinical course was characterized by a violation of the menstrual cycle in 55% of women and infertility was observed in 100%.

Ключевые слова

polyp, infertility, intrauterine pathology, endometrium, hysteroscopy.

Литературы

1. Айламазян, Эдуард Карпович, et al. "Особенности экспрессии рецепторов половых стероидных гормонов, провоспалительных маркеров и ингибитора циклин-зависимой киназы p16ink4a в эндометрии при наруж-ном генитальном эндометриозе." Журнал акушерства и женских болезней 65.3 (2016). 2. Кинаятова, Ш., et al. "Клинико-морфологические особенности эндометриальных полипов у женщин в воз-растном аспекте." InterConf (2021): 823-832. 3. Г. Т. Раббимова, Б. Б. Негмаджанов, Н. Р. Насимова, З. С. Насимова, М. О. Сонокулова Кесар кесиш опера-циясидан кейин пайдо бўлган ―ниша‖ симптоми ва бепуштлик // Доктор ахборотномаси, № 3 (100), 2021. С.143-148. DOI: 10.38095/2181-466X-20211003-143-148 4. Салихова, Тамара Руслановна, and Наби Султан-Мурадович Омаров. "Роль гипоксии в патогенезе развития эндометриальных полипов в постменопаузе." Современная наука: актуальные проблемы теории и практи-ки. Серия: Естественные и технические науки 9 (2018): 88-93. 5. Al Chami, Ali, and Ertan Saridogan. "Endometrial polyps and subfertility." The Journal of Obstetrics and Gyne-cology of India 67.1 (2017): 9-14. 6. American Association of Gynecologic Laparoscopists (AAGL): Advancing Minimally Invasive Gynecology Worldwide. "AAGL practice report: practice guidelines for the diagnosis and management of submucous leiomyo-mas." Journal of minimally invasive gynecology 19.2 (2012): 152-171. 7. Balcacer, Patricia, et al. "Magnetic resonance imaging features of endometrial polyps: frequency of occurrence and interobserver reliability." Journal of computer assisted tomography 42.5 (2018): 721-726. 8. Bouet, Pierre-Emmanuel, et al. "Chronic endometritis in women with recurrent pregnancy loss and recurrent im-plantation failure: prevalence and role of office hysteroscopy and immunohistochemistry in diagnosis." Fertility and sterility 105.1 (2016): 106-110. 9. Cahill, Michael A., et al. "The emerging role of progesterone receptor membrane component 1 (PGRMC1) in can-cer biology." Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1866.2 (2016): 339-349. 10. Centini, Gabriele, et al. "Modern operative hysteroscopy." Minerva ginecologica 68.2 (2016): 126-132. 11. Cholkeri-Singh, Aarathi, and Kirsten J. Sasaki. "Hysteroscopy for infertile women: a review." Journal of minimal-ly invasive gynecology 22.3 (2015): 353-362. 12. Clark, T. Justin, and Helen Stevenson. "Endometrial Polyps and Abnormal Uterine Bleeding (AUB-P): What is the relationship, how are they diagnosed and how are they treated?." Best Practice & Research Clinical Obstetrics & Gynaecology 40 (2017): 89-104. 13. Doria, Pedro Leopoldo Silva, et al. "Association of IGF-1 CA (n) and IGFBP3 rs2854746 polymorphisms with endometrial polyp risk." BioMed research international 2018 (2018). 14. Drobyazko, P. A. "PREVIEW OF FOREIGN CLINICAL GUIDELINES FOR HYSTEROSCO-PY." Международный научно-исследовательский журнал (2021). 15. Fang, Rui-Li, et al. "Barcoded sequencing reveals diverse intrauterine microbiomes in patients suffering with en-dometrial polyps." American journal of translational research 8.3 (2016): 1581. 16. Fadare, Oluwole, Idris L. Renshaw, and Vinita Parkash. "The spectrum of morphologic alterations associated with infarction in endometrial polyps: a report of 41 cases." International Journal of Gynecological Pathology 38.1 (2019): 32-43. 17. Guo, Tao, et al. "Identifying the superior surgical procedure for endometrial polypectomy: A network meta-analysis." International Journal of Surgery 62 (2019): 28-33. 18. Horsburgh, Steven, et al. "Exercise and inflammation-related epigenetic modifications: focus on DNA methyla-tion." Exercise immunology review 21 (2015). 19. Jeon, Se Jeong, et al. "Endometrial polyp surveillance in premenopausal breast cancer patients using tamoxi-fen." Obstetrics & gynecology science 60.1 (2017): 26. 20. Karakuş, S. S., et al. "Reproductive outcomes following hysteroscopic resection of endometrial polyps of different location, number and size in patients with infertility." Journal of Obstetrics and Gynaecology 36.3 (2016): 395-398. 21. Ludwin, Artur, et al. "Removal of uterine polyps: clinical management and surgical approach." Climacteric 23.4 (2020): 388-396 22. Luerti, Massimo, et al. "Effectiveness of hysteroscopic techniques for endometrial polyp removal: the Italian mul-ticenter trial." Journal of minimally invasive gynecology 26.6 (2019): 1169-1176. 23. Malhotra, Narendra, and Nitin Shah. "Hysteroscopy and Endometrial Polyps." Hysteroscopy Simplified by Mas-ters. Springer, Singapore, 2021. 91-98. 24. Manchanda, Rahul, and Richa Sharma. "How to Set up High-Tech Hysteroscopy Unit." Hysteroscopy Simplified by Masters. Springer, Singapore, 2021. 27-37 25. Matei, Alexandra, et al. "Insights on Hysteroscopic Procedures and Their Place in Romanian Gynecologic Prac-tice—The Experience of Two Medical Units." Diagnostics 10.5 (2020). 26. Metello, José, and João Mairos. "Uterine Polyps." Atlas of Hysteroscopy. Springer, Cham, 2020. 41-54. 27. Munro, Malcolm G., et al. "The two FIGO systems for normal and abnormal uterine bleeding symptoms and clas-sification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions." International Journal of Gynecology & Obstetrics 143.3 (2018): 393-408. 28. Murdock, Tricia A., et al. Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach. Springer, 2018. 29. Ouyang, Chensi, et al. "Malignant Endometrial Polyps in Uterine Serous Carcinoma: The Prognostic Value of Pol-yp Size and Lymphovascular Invasion." International Journal of Gynecologic Cancer 28.3 (2018). 30. Režňák, Lukáš, and Milan Kudela. "Comparison of ultrasound with hysteroscopic and histological findings for intrauterine assessment." Biomedical Papers (2018). 31. Safdar, Nida S., Giovanna A. Giannico, and Mohamed Mokhtar Desouki. "Utility of a standardized protocol for submitting clinically suspected endometrial polyps to the pathology laboratory." Annals of diagnostic patholo-gy 23 (2016): 29-31. 32. Salazar, Christina, et al. "Hysteroscopy: 0ffice and Operative-Myomectomy, Polypectomy, and Adhesioly-sis." Reproductive Surgery: The Society for Reproductive Surgeons' Manual (2018): 1. 33. Sharma, Sangita. "Polyps: Hysteroscopic Diagnosis and Management." Manual of Fertility Enhancing Hysterosco-py. Springer, Singapore, 2018. 61-78 34. Smith, Paul, and T. Justin Clark. "Hysteroscopic Endometrial Polypectomy." Diagnostic and Operative Hyster-oscopy (2020): 118 35. Stamenov, Georgi Stamenov, et al. "Hysteroscopy and female infertility: a fresh look to a busy corner." Human Fertility (2020): 1-29. 36. Teresiński, Leszek, et al. "Assessment of morphological changes and steroid receptors in the uteri of postmeno-pausal women." Histology and histopathology 34.6 (2018): 631-644. 37. Troncon, Júlia Kefalas, et al. "Endometrial Polyps-When Should Hysteroscopic Resection Be Per-formed?." Revista Brasileira de Ginecologia e Obstetrícia 38.7 (2016): 315-316 38. Vander Borght, Mélodie, and Christine Wyns. "Fertility and infertility: Definition and epidemiology." Clinical biochemistry 62 (2018): 2-10. 39. Wang, Yue, et al. "Prevention of Benign Endometrial Polyp Recurrence Using a Levonorgestrel-releasing Intrau-terine System in Premenopausal Patients: A Retrospective Cohort Study." Journal of Minimally Invasive Gynecol-ogy 27.6 (2020): 1281-1286 40. Yen, Chih-Feng, et al. "Effectiveness and appropriateness in the application of office hysteroscopy." Journal of the Formosan Medical Association 118.11 (2019): 1480-1487 41. Zhang, YunZheng, et al. "Deep learning model for classifying endometrial lesions." Journal of Translational Medi-cine 19.1 (2021): 1-13.