Kardiorespirator tadqiqotlar jurnali. Maxsus son. 2022
Тема статьи
STABIL BO'LMAGAN STENOKARDIYA BILAN OG'RIGAN BEMORLARDA PSIXOSOMATIK XAVF OMILLARINING XUSUSIYATLARI (97-105)
Авторы
Nasirova Z.A., Abdulloeva M.D., Ochilov U.U.
Учреждение
Samarqand Davlat Tibbiyot Universiteti
Аннотация
Stabil angina bilan og'rigan 138 nafar bemor tanlab olindi. O'rtacha yoshi 61,34±12,26 yoshni tashkil etdi. Bemorlar orasida erkak jinsi ustunlik qildi va 56% (n= 78) ni tashkil etdi. Respublika shoshilinch tibbiy yordam ilmiy markazi Samarqand filiali, 1, 2-sonli shoshilinch terapiya va somatik reanimatsiya bo‘limlarida bemorlar tanlab olindi. Ushbu ishda taqdim etilgan zamonaviy laboratoriya diagnostika usullari SAPR destabilizatsiyasi rivojlanishining patogenezida psixosomatik testlar, instrumental tadqiqotlar va biokimyoviy mexanizmlarning ishtiroki muhimligini tasdiqladi, bu esa o'z navbatida davolashga takomillashtirilgan va shaxsiylashtirilgan yondashuvga yordam beradi. ushbu patologik holatning oldini olish, shuningdek, prognozni yaxshilash va yurak-qon tomir asoratlari va o'limni kamaytirish. Psixoemosional buzilish bilan birga keladigan NS bilan og'rigan bemorlar yurak-qon tomir kasalliklari va kam omon qolish tufayli tez-tez kasalxonaga yotqizilishi bilan tavsiflanadi. Surunkali koroner yurak kasalligi bo'lgan bemorlar uchun MPQ sensorli shkalasiga asoslangan so'rov beqaror angina va PEB bilan og'rigan bemorlarda yanada kuchli og'riq sindromlarini aniqladi.
Ключевые слова
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Литературы
1. A. Abdi-Ali, A. Shaheen, D. Southern, et al. Relation between family history of premature coronary artery disease and the risk of death in patients with coronary artery disease Am J Cardiol, 117 (3) (2016), pp. 353-358 2. A. Levi, C. Chezar-Azerrad, D. Hasdai, et al. Impact of self-reported family history of premature cardiovascular disease on the outcomes of patients hospitalized for acute coronary syndrome (from the acute coronary syndrome Israel survey [ACSIS] 2000 to 2013) Am J Cardiol, 122 (6) (2018), pp. 917-921 3. A. Singh, A. Gupta, B.L. Collins, et al. Familial hypercholesterolemia among young adults with myocardial infarction J Am Coll Cardiol, 73 (19) (2019), pp. 2439-2450 4. A.B. Jørgensen, R. Frikke-Schmidt, B.G. Nordestgaard, A. Tybjærg-Hansen Loss-of-function mutations in APOC3 and risk of ischemic vascular disease N Engl J Med, 371 (1) (2014), pp. 32-41 5. A.V. Khera, S. Kathiresan Genetics of coronary artery disease: discovery, biology and clinical translation Nat Rev Genet, 18 (6) (2017), pp. 331-344 6. C.A. Emdin, A.V. Khera, D. Klarin, et al. Phenotypic consequences of a genetic predisposition to enhanced nitric oxide signaling Circulation, 137 (3) (2018), pp. 222-232 7. C.B. Cole, M. Nikpay, A.F. Stewart, R. McPherson 8. F.B. Ortega, C.J. Lavie, S.N. Blair Obesity and cardiovascular disease Circ Res, 118 (11) (2016), pp. 1752-1770 9. G.B. Ehret, T. Ferreira, D.I. Chasman, et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals Nat Genet, 48 (10) (2016), pp. 1171-1184 10. H. Pang, Z. Zong, L. Hao, Q. Cao ABO blood group influences risk of venous thromboembolism and myocardial infarction J Thromb Thrombolysis, 50 (2) (2020), pp. 430-438 11. H. Poorzand, K. Tsarouhas, S.A. Hozhabrossadati, et al. Risk factors of premature coronary artery disease in Iran: a systematic review and meta-analysis 12. H. Schunkert Family or SNPs: what counts for hereditary risk of coronary artery disease Eur Heart J, 37 (6) (2016), pp. 568-571 13. H. Tada, O. Melander, J.Z. Louie, et al. Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history 14. H. Wang, Z. Liu, J. Shao, et al. Immune and inflammation in acute coronary syndrome: molecular mechanisms and therapeutic implications J Immunol Res, 2020 (2020), p. 4904217 15. I. Brænne, M. Kleinecke, B. Reiz, et al. Systematic analysis of variants related to familial hypercholesterolemia in families with premature myocardial infarction Eur J Hum Genet, 24 (2) (2016), pp. 191-197 16. J.P. Collet, M. Zeitouni, N. Procopi, et al. Long-term evolution of premature coronary artery disease J Am Coll Cardiol, 74 (15) (2019), pp. 1868-1878 17. L. Chen, H. Qian, Z. Luo, et al. PHACTR1 gene polymorphism with the risk of coronary artery disease in Chinese Han population Postgrad Med J, 95 (1120) (2019), pp. 67-7118. M. Nikpay, A. Goel, H.H. Won, et al.A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease Nat Genet, 47 (10) (2015), pp. 1121-1130 19. M.S. Sabatine, R.P. Giugliano, A.C. Keech, et al. Evolocumab and clinical outcomes in patients with cardiovascular disease N Engl J Med, 376 (18) (2017), pp. 1713-1722 20. Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, N.O. Stitziel, K.E. Stirrups, et al. Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease N Engl J Med, 374 (12) (2016), pp. 1134-1144 21. Myocardial Infarction Genetics Consortium Investigators, N.O. Stitziel, H.H. Won, et al. Inactivating mutations in NPC1L1 and protection from coronary heart disease N Engl J Med, 371 (22) (2014), pp. 2072-2082 22. O. Bilen, Y. Pokharel, C.M. Ballantyne Genetic testing in hyperlipidemia Cardiol Clin, 33 (2) (2015), pp. 267-275 23. P. Nioi, A. Sigurdsson, G. Thorleifsson, et al. Variant ASGR1 associated with a reduced risk of coronary artery disease N Engl J Med, 374 (22) (2016), pp. 2131-2141 24. P. van der Harst, N. Verweij Identification of 64 novel genetic loci provides an expanded view on the genetic architecture of coronary artery disease 25. P.M. Ridker From CANTOS to CIRT to COLCOT to clinic: will all atherosclerosis patients soon Be treated with combination lipid-lowering and inflammation-inhibiting agents Circulation, 141 (10) (2020), pp. 787-789 P.M. Ridker, B.M. Everett, T. Thuren, et al.Antiinflammatory therapy with canakinumab for atherosclerotic disease 26. R. Do, N.O. Stitziel, H.H. Won, et al. 27. R. Posadas-Sánchez, N. Pérez-Hernández, J. Angeles-Martínez, et al. 28. R. Roberts Genetic risk stratification: tipping point for global primary prevention of coronary artery disease Circulation, 137 (24) (2018), pp. 2554-2556 29. R.M. Gupta, J. Hadaya, A. Trehan, et al. A genetic variant associated with five vascular diseases is a distal regulator of endothelin-1 gene expression 30. S. Sandler, L. Alfino, M. Saleem The importance of preventative medicine in conjunction with modern day genetic studies Genes Dis, 5 (2) (2018), pp. 107-111 31. S. Thériault, R. Lali, M. Chong, J.L. Velianou, M.K. Natarajan, G. Paré Polygenic contribution in individuals with early-onset coronary artery disease 32. S.D. Kumbhalkar, V.V. Bisne Clinical and angiographic profile of young patients with ischemic heart disease: a central India study J Clin Prev Cardiol, 8 (2019), pp. 6-12 33. T. Li, L. Ding, Y. Wang, O. Yang, S. Wang, J. Kong Genetic deficiency of Phactr1 promotes atherosclerosis development via facilitating M1 macrophage polarization and foam cell formation Clin Sci (Lond)., 134 (17) (2020), pp. 2353-2368 34. T.L. Assimes, D.M. Herrington Genetic risk scores in premature coronary artery disease: still only one piece of the prevention puzzle Circ Genom Precis Med, 11 (1) (2018), Article e002006 35. T.L. Assimes, R. Roberts Genetics: implications for prevention and management of coronary artery disease J Am Coll Cardiol, 68 (25) (2016), pp. 2797-2818 36. Y. Abramowitz, A. Roth, G. Keren, et al. Whole-exome sequencing in individuals with multiple cardiovascular risk factors and normal coronary arteries Coron Artery Dis, 27 (4) (2016), pp. 257- 266 37. Y. Okuyama, N. Hirawa, M. Fujita, et al. The effects of anti-hypertensive drugs and the mechanism of hypertension in vascular smooth muscle cell-specific ATP2B1 knockout mice Hypertens Res, 41 (2) (2018), pp. 80-87